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Micronutrients, Health and Disease
There’s a good reason so many health-conscious consumers rely on supplements: supplementation has numerous health benefits and minimizes the risk of many common diseases. The scientific literature is overflowing with studies showing the health benefits of supplements, as well as their disease-preventing effects: [1,2,3,4,5,6,7,8,9,10,11,12,13,14,15,16,17,18,19,20,21,22,23,25,26,27,28,29,30]. (For more scientific references about micronutrients' health-promoting and disease-preventing benefits, please refer to Healthy Past 100 by Dr. Steven Teagarden.)
The Many Measures of Health
Health is assessed in many ways; key health measures include lifespan, healthspan, healthy aging, health-related quality of life, and all-cause mortality. These terms are defined as:
• Lifespan—the span of time between birth and death
• Healthspan—the span of time prior to developing chronic diseases like cancer and heart disease
• Healthy aging—the continuance of a high degree of function and wellness into advanced age
• Health-related quality of life—a sense of deep satisfaction with your day-to-day life
• All-cause mortality—the risk of death from any and all causes
Importantly, the appropriate use of dietary supplements can positively affect all of these crucial health measures [31,32,33,34,35,36,37,38,39,40,41,42]. That’s impressive! Everyone has wondered if taking supplements is important, but it’s only in recent years that science has shown just how important supplements are to our health. Taking the right supplements can positively affect how long you live and minimize the risks of succumbing to modern diseases. Nutrition is powerful medicine; providing your cells with the required micronutrients is crucial to your health and wellbeing.
Marginal Micronutrient Deficiencies are Common
Due to their numerous health-sustaining properties, micronutrients are added to everyday foods. These foods are known as fortified foods. Even so, many who regularly consume fortified foods develop marginal micronutrient deficiencies[43]. Marginal micronutrient deficiencies occur when the cellular uptake of essential micronutrients, such as vitamins B1 and C, become slightly deficient. These deficiencies arise in response to inadequate micronutrient intake, stress, rushed meals, alcohol and coffee consumption, single nucleotide polymorphisms (SNPs), and many other prevalent factors in the modern world[44].
Marginal micronutrient deficiencies can cause chronic diseases, a lack of overall well-being, fatigue, impaired immunity, impaired memory, poor concentration, limited attention span, impaired mood, and decreased physical performance[45].
Humans are commonly deficient in several key micronutrients, making supplementation essential for optimal health. Unfortunately, the US Recommended Daily Allowance (RDA) for several essential micronutrients is notoriously low, and many Americans consume micronutrients in amounts below this already low threshold. The figures below show the percentage of Americans deficient in common essential micronutrients.
Percentage of Americans Deficient in Common Essential Micronutrients
Vitamin A 56.2%
Vitamin B1 (Thiamine) 30.2%
Vitamin B2 (Riboflavin) 2.4%
Vitamin B3 (Niacin) 25.9%
Vitamin B4 (Choline) 91.7%
Vitamin B6 (Pyridoxine) 53.6%
Vitamin B9 (Folate) 33.2%
Vitamin B12 (Cobalamin) 17.2%
Vitamin C 42.9%
Vitamin D 95.4%
Vitamin E 93.9%
Vitamin K 71.1%
Calcium 65.1%
Copper 4.2%
Iodine Widespread
Iron 39.1%
Magnesium 68%
Phosphorus 27.4%
Potassium 100%
Selenium 1.1%
Zinc 73.3%
The above figures excerpted from Healthy Past 100 by Dr. Steven Teagarden
Source:[[46],[47],[48],[49]]
The above figures show only some of the micronutrients that humans commonly lack, because many micronutrients have yet to be extensively studied. When fortified cereals and other processed foods are eliminated from the diet, humans may become deficient in Vitamin B2 (riboflavin), making it necessary to supplement with this essential micronutrient. The data is clear and resoundingly states that nutrient deficiencies are the rule, not the exception. This makes supplementation a necessity, not a luxury.
The Heart, Kidneys, Brain and Liver Require More Micronutrients
The heart, kidneys, brain and liver (in that order) are the most metabolically active organs in the body[50]. To fuel their high metabolic demands, these organs create much more energy (ATP) each day than other parts of the body. ATP (adenosine triphosphate) is the fuel your cells create to power their functions. ATP is produced around the clock in the trillions of mitochondria in your body. Your mitochondria churn out as much ATP each day as you weigh; active individuals create twice (or more) their body weight in ATP. The heart alone creates 6 kilograms of ATP daily (13.23 pounds) to pump blood[51]. That’s a lot of ATP!
This is super important, because your mitochondria need a lot of micronutrients to make the ATP that powers your cells. The entire body requires micronutrients to generate a steady supply of ATP, and this is particularly true for the heart, kidneys, brain and liver. It’s estimated that mitochondria make up 40% of typical heart cells and 25% of typical liver cells. This gives some idea of how much energy these organs need each day, which is why providing them with an abundance of the micronutrients they require is essential.
The Heart, Kidneys, Brain and Liver Store Micronutrients
To ensure that the heart, kidneys, brain and liver have enough micronutrients to generate large amounts of ATP, they store several micronutrients in amounts more significant than the rest of the body. For example, the kidneys store vitamin A, iron, selenium, vitamins B2, B5, B6, and large amounts of vitamin B12. The brain stores DHA, B vitamins, vitamin A, vitamin C, vitamin D and vitamin E. Tightly regulated homeostatic mechanisms allow the brain to retain four times more vitamin B9 and 50 times more vitamin B5 (pantothenic acid) and vitamin B7 (biotin) than in the blood[52].
Micronutrient Deficiencies Cause Heart, Kidney, Brain and Liver Disease
It’s also important to note that micronutrient deficiencies are associated with increased diseases of the heart, kidneys, brain and liver. Due to the high metabolic demands of these organs, they require significantly more of the micronutrients that support ATP production. Micronutrients necessary to generate ATP include all the B vitamins, vitamins C, D, and E, iron, magnesium, copper, zinc, manganese, selenium, phosphorus and calcium[53]. There is also evidence that vitamin A plays a crucial role in ATP creation[54], and that betaine (trimethylglycine) plays a modulatory role in the production of ATP[55].
Neuroprotection: Where Supplements and Science Meet
Of great concern is the rapid rise of neurodegenerative diseases in recent decades. These diseases include Alzheimer's disease, amyotrophic lateral sclerosis (ALS), multiple sclerosis (MS), Parkinson's disease, Huntington's disease, multiple system atrophy, tauopathies, and prion diseases. Remarkably, micronutrients have been shown to slow the progression of already-existing neurodegenerative conditions[56,57,58,59,60].
Although the heart is considered the most metabolically active organ, the brain, which comprises 2% of total body weight, consumes 20% of our daily energy; all in all, the brain produces a whopping 5.7kg (12.57 pounds) of ATP each day[61]. Thus, micronutrient deficiencies can impair the central nervous system's ATP production and produce excess oxidative stress in the body and brain[62,63,64]. Oxidative stress, which occurs when excess oxygen free radicals are produced in the mitochondria, is hypothesized to underlie aging and death[65]. Micronutrient deficiencies, particularly vitamin B12, cause an elevation of homocysteine, which is strongly implicated in the development of neurodegenerative diseases[66].
Thus micronutrient deficiencies can result in neurodegenerative diseases in various ways. Super Empowered Supplements has scoured the scientific literature to determine which micronutrient deficiencies are associated with neurodegenerative diseases, and have included these key nutrients in amounts sufficient to provide neuroprotective effects.
Micronutrient Deficiencies Are Associated With Neuropsychiatric Diseases
Just as micronutrient deficiencies are associated with neurodegenerative diseases, they are also associated with psychiatric diseases and mood disorders[67,68,69]. Our Super All-In-One Supplement Formula is rich in the micronutrients that improve mood, helping you to live your best life.
Let Cutting-Edge Research Guide Your Supplement Purchases
When it comes to science, we’ve done our homework. We’ve read thousands of top-quality studies demonstrating the health benefits of taking high-quality supplements. A few examples are included here: [69,70,71,72,73,74,75,76,77,78,79,80,81,82,83,84,85,86,87,88,89,90]. The research is in, and it conclusively shows that supplementing with micronutrients improves your health and minimizes the risk of developing common diseases.
Investing money in supplements and other healthcare products is based on what makes sense to your mind and what feels right in your body. We’ve carefully designed our Super All-In-One formula to do both. It’s important to know that you’re purchasing the highest-quality products, ones whose formulations are based on rigorous research to ensure your long-term health and wellbeing—and that you can actually feel working in your body.
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